Saponin-based adjuvants enhance antigen cross-presentation in human CD11c + CD1c + CD5 - CD163 + conventional type 2 dendritic cells.
Nataschja I HoLisa G M Huis In 't VeldJesper van Eck van der SluijsBranco M H HeutsMaaike W G LoomanEsther D Kers-RebelKoen van den DriesHarry DolstraJoost H A MartensWillemijn HoboGosse J AdemaPublished in: Journal for immunotherapy of cancer (2023)
cDC2 subset as the main SBA-responsive DC subset in humans and imply new strategies to optimize the application of saponin-based adjuvants in a potent cancer vaccine.