Pomegranate Extract Improves Colitis in IL-10 Knockout Mice Fed a High Fat High Sucrose Diet.
Jieping YangPatrizia Maria GermanoSuwan OhSijia WangJing WangRupo LeeHayden PaigeScarlet YangSusanne M HenningJin ZhongJonathan P JacobsZhaoping LiPublished in: Molecular nutrition & food research (2022)
The data demonstrate that dietary PomX supplementation ameliorated colitis and lowered inflammatory markers in HFHS fed IL-10-/- mice. These data support the anti-inflammatory effects of dietary PomX supplementation for IBD and a potential mediating role of gut microbiome, suggesting the need for future clinical studies to explore the use of PomX dietary supplementation in IBD patients.
Keyphrases
- anti inflammatory
- end stage renal disease
- ulcerative colitis
- electronic health record
- newly diagnosed
- ejection fraction
- chronic kidney disease
- physical activity
- prognostic factors
- type diabetes
- current status
- risk assessment
- high fat diet induced
- patient reported outcomes
- artificial intelligence
- adipose tissue
- deep learning