Zim CHIC: A cohort study of immune changes in the female genital tract associated with initiation and use of contraceptives.

Sharon L AchillesLeslie A MeynFelix G MhlangaAllen T MatubuKevin A StonerMay A BeamerZvavahera M ChirenjeSharon L Hillier

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2020)

This head-to-head study compared six contraceptives and found increased HIV target cells and cervical inflammation temporally associated with Cu-IUD initiation. Use of hormonal contraception, including DMPA, did not increase cervical HIV target cells or inflammation. Clinical Trial Number: NCT02038335.

Keyphrases

induced apoptosis
clinical trial
antiretroviral therapy
oxidative stress
hiv positive
hiv infected
cell cycle arrest
human immunodeficiency virus
hiv testing
hepatitis c virus
hiv aids
men who have sex with men
endoplasmic reticulum stress
type diabetes
south africa
signaling pathway
cell proliferation
phase iii