Login / Signup

The airway microbiome in COPD, bronchiectasis and bronchiectasis-COPD overlap.

Pei Yee TiewTavleen K JaggiLouisa L Y ChanSanjay Haresh Chotirmall
Published in: The clinical respiratory journal (2020)
Use of next-generation sequencing has revolutionised our detection and understanding of the airway microbiome in chronic respiratory diseases such as COPD and bronchiectasis. Targeted amplicon sequencing reveals important associations between the respiratory microbiome and disease outcome while metagenomics may elucidate functional pathways. How best to apply this information into patient care, monitoring and treatment, however, remains challenging and necessitates further study.
Keyphrases
  • cystic fibrosis
  • lung function
  • chronic obstructive pulmonary disease
  • copy number
  • air pollution
  • respiratory tract
  • health information
  • label free
  • loop mediated isothermal amplification
  • cell free