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Vertebrobasilar Dolichoectasia, Hypoplastic Third Ventricle, and Related Biventricular Hydrocephalus: Case Report and Review of the Literature.

Giuseppe Emmanuele Emmanuele UmanaNicola AlberioFrancesca GrazianoMarco FriciaSantino Ottavio TomasiLeonardo CorbinoGiovanni Federico NicolettiSalvatore CiceroGianluca Scalia
Published in: Journal of neurological surgery. Part A, Central European neurosurgery (2021)
 The natural clinical history of patients affected by VBDE is unfavorable with 7.8 years of median survival. The therapeutic strategy is usually conservative and the role of antiplatelets or oral anticoagulants is still debated. In selected patients, ventriculoperitoneal shunt to resolve intracranial hypertension caused by biventricular hydrocephalus is the most effective treatment. In our opinion, chronic third ventricle compression could lead to anatomic-pathologic alterations like the third ventricle hypoplasia documented in our report.
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