Abolishing β-arrestin recruitment is necessary for the full metabolic benefits of G protein-biased glucagon-like peptide-1 receptor agonists.
Charlotte E HindsEllie PeaceShiqian ChenIona DaviesLiliane El EidAlejandra TomasTricia Mei-Mei TanJames MinnionBen J JonesStephen R BloomPublished in: Diabetes, obesity & metabolism (2023)
Completely abolishing β-arrestin recruitment improves the anti-hyperglycaemic effects of GLP-1R agonists in mice.