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Alkaloids Extract from Linum usitatissimum Attenuates 12-OTetradecanoylphorbol- 13-Acetate (TPA)-induced Inflammation and Oxidative Stress in Mouse Skin.

Mohamed Sofiane MerakebNoureddine BribiRiad FerhatMeriem AziezBetitera Yanat
Published in: Anti-inflammatory & anti-allergy agents in medicinal chemistry (2023)
These findings suggest that the total alkaloid extract from Linum usitatissimum seeds presents significant anti-inflammatory and anti-oxidant effects on TPA-induced sub-chronic inflammation model in NMRI mice and can be used as an anti-inflammatory and anti-oxidant agent for the therapeutic management of inflammatory disorders.
Keyphrases
  • oxidative stress
  • anti inflammatory
  • diabetic rats
  • high glucose
  • ischemia reperfusion injury
  • dna damage
  • induced apoptosis
  • drug induced
  • adipose tissue
  • heat shock
  • signaling pathway
  • insulin resistance
  • skeletal muscle