Characterization of Immune-Related Genes and Immune Infiltration Features in Epilepsy by Multi-Transcriptome Data.

Yunqi HouZhen ChenLiping WangYingxin DengGenglong LiuYongfen ZhouHaiqin ShiXiangqun ShiQianhua Jiang

Published in: Journal of inflammation research (2022)

Four IRGs (CSF1R, IL6R, TLR2, and TNFRSF1A) were closely correlated pathogenesis of epilepsy, which may be by impacting CCR and the balance of Th1/Th2 signatures involved in the occurrence of epilepsy. Our data offer compelling insights into the pathogenesis and promising therapeutic targets for epilepsy.

Keyphrases

electronic health record
risk assessment
genome wide
big data
toll like receptor
inflammatory response
gene expression
single cell
temporal lobe epilepsy
immune response
rna seq
dendritic cells
deep learning
data analysis