Nanoparticle probes for quantifying supramolecular determinants of biosurface affinity.

N D B LeS HouG Y TongaH A JerriS G ElciT MizuharaV NormandD BenczédiR W VachetV M Rotello

Published in: Particle & particle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems (2017)

Interactions between macromolecular systems and biosurfaces are complicated by both the complexity of these multivalent interactions and challenges in quantifying affinities. A library of gold nanoparticles (AuNPs) as multivalent probes is used to quantify biosurface affinity, using hair as a model targeted substrate.

Keyphrases

gold nanoparticles
small molecule
living cells
fluorescence imaging
single molecule
capillary electrophoresis
cancer therapy
reduced graphene oxide
nucleic acid
fluorescent probe
photodynamic therapy
energy transfer
drug delivery