Microarray analysis of distinct gene transcription profiles in non-eosinophilic chronic sinusitis with nasal polyps.

Spencer C PayneJoseph K HanPhillip HuyettJulie NegriElizabeth Z KropfLarry BorishJohn W Steinke

Published in: American journal of rhinology (2009)

This study explores the utility of gene microarray technology in identifying unexplored targets of immune dysregulation in NE-CRSwNP. Furthermore, the data characterize the immunologic profile of NE-CRSwNP as it differs from other forms of CRSwNP, in particular, those known to be associated with eosinophilic inflammation.

Keyphrases

chronic rhinosinusitis
copy number
genome wide

oxidative stress
genome wide identification
transcription factor

big data
gene expression
machine learning

data analysis
deep learning
bioinformatics analysis