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Cytoreductive treatment in real life: a chart review analysis on 1440 patients with polycythemia vera.

Carl C CrodelKathleen Jentsch-UllrichMarcel ReiserLutz JacobaschAnnette SauerHans TeschThomas UlshöferRegine WunschelFrancesca PalandriFlorian H Heidel
Published in: Journal of cancer research and clinical oncology (2021)
Cytoreductive treatment of high-risk PV in real life is highly variable regarding indication for cytoreduction and definition of therapy resistance. This study highlights the need for (i) improved risk stratification for thromboembolic events, (ii) consequent indication of pharmacologic cytoreduction in high-risk PV and (iii) attention to signs of therapy resistance that can trigger an earlier and stringent switch to second line agents.
Keyphrases
  • stem cells
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  • atrial fibrillation