Thrombotic microangiopathy due to acquired complement factor I deficiency in a male receiving interferon-beta treatment for multiple sclerosis.

Sanda MrabetRihem DahmaneBoukadida RajaAsma FradiNarjess Ben AichaWissal SahtoutAwatef AzzabiYosra GuedriDorsaf ZellamaAbdellatif AchourImen SfarRim GouchaNihed AbdessayedMoncef Mokni

Published in: British journal of clinical pharmacology (2022)

IFNβ treatment may cause complement factor I deficit, which can lead to thrombotic microangiopathy and severe renal failure.

Keyphrases

multiple sclerosis
dendritic cells
early onset
combination therapy