Relationship of sputum mast cells with clinical and inflammatory characteristics of asthma.
Michael FrickerLing QinNatalie NiessenKatherine J BainesVanessa M McDonaldHayley A ScottJodie Louise SimpsonPeter G GibsonPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2020)
Sputum MCs are elevated in asthma, and their measurement may be useful as they relate to key clinical features of asthma (spirometry, asthma control, AHR). PBE count did not predict airway MC status, suggesting direct measurement of airway MCs by sensitive methods such as flow cytometry should be further developed.