Implementation of a Consensus Set of Hypervariable Mycobacterial Interspersed Repetitive-Unit-Variable-Number Tandem-Repeat Loci in Mycobacterium tuberculosis Molecular Epidemiology.

Alberto TrovatoSilva TafajSimone BattagliaRiccardo AlagnaDonika BardhiPerlat KapisyziSilvana BalaMigena HaldedaEmanuele BorroniHasan HafiziDaniela Maria Cirillo

Published in: Journal of clinical microbiology (2015)

This study shows that the addition of a consensus 4-locus set of hypervariable mycobacterial interspersed repetitive-unit-variable-number tandem repeat (MIRU-VNTR) loci to the spoligotyping-24-locus MIRU-VNTR typing strategy is a well-standardized approach that can contribute to an improvement of the true cluster definition while retaining high typeability in non-Beijing strains.

Keyphrases

mycobacterium tuberculosis
genome wide association study
high frequency
genome wide
pulmonary tuberculosis
primary care
healthcare
clinical practice
genome wide association
air pollution
particulate matter
gene expression
dna methylation
genetic diversity