Patient-derived bladder cancer organoids show stable transcript expression along cultivation.
Philipp VollmerBastian AmendNiklas HarlandArnulf StenzlIgor TsaurMoritz MaasWilhelm K AicherSimon WalzPublished in: World journal of urology (2024)
The robust transcriptome during BCO cultivation advocates for the use of earlier passages of BCOs in personalized medicine providing a time-efficient drug screening option to accelerate the counseling of patients' treatment options. Higher passages of BCOs still hold the potential in topics demanding for expanded cell masses such as medical device development and others.