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Patient-derived bladder cancer organoids show stable transcript expression along cultivation.

Philipp VollmerBastian AmendNiklas HarlandArnulf StenzlIgor TsaurMoritz MaasWilhelm K AicherSimon Walz
Published in: World journal of urology (2024)
The robust transcriptome during BCO cultivation advocates for the use of earlier passages of BCOs in personalized medicine providing a time-efficient drug screening option to accelerate the counseling of patients' treatment options. Higher passages of BCOs still hold the potential in topics demanding for expanded cell masses such as medical device development and others.
Keyphrases
  • end stage renal disease
  • single cell
  • rna seq
  • newly diagnosed
  • ejection fraction
  • chronic kidney disease
  • healthcare
  • gene expression
  • prognostic factors
  • computed tomography
  • risk assessment