Incidence of chromosomal abnormalities in fetuses with first trimester ultrasound anomalies and a low-risk cell-free DNA test for common trisomies.
Nicola PersicoSimona BoitoPaolo VolpeBenedetta IschiaMattia GentileLuisa RonzoniValentina De RobertisIsabella FabiettiClaudiana OlivieriEnrico PeritiRomina FicarellaRosamaria SilipigniGeorgios RembouskosPublished in: Prenatal diagnosis (2020)
In fetuses with first trimester ultrasound anomalies and a low-risk cfDNA result for trisomy 21, 18 and 13, diagnostic testing should be offered with the main objective to detect chromosomal abnormalities beyond common trisomies.