Unusual renal displacement due to massive splenomegaly: a rare case report and review of literature.
Zhihua HeWuhao LiuJiafu XiaoGuancheng XiaoPublished in: The Journal of international medical research (2024)
Here, the case of a female patient in her late 60s, who presented to hospital for a scheduled health check relating to a history of myelofibrosis for the previous 9 years, is described. She recently experienced weight loss and abdominal distention. Physical examination revealed no abnormality or tenderness. Laboratory examination showed decreased blood cells, platelets and haemoglobin, and normal renal function. Ultrasound and computed tomography scans revealed a massively enlarged spleen and displaced and compressed left kidney with abnormal features, but normal right kidney. The patient declined surgery and her myelofibrosis was treated with ruxolitinib, with a recommendation of annual follow-up observation. Despite many recorded cases of left renal displacement caused by splenomegaly, it is very rare for the left kidney to be pushed across the midline to the right side by an enlarged spleen. This article explores the causes and management of this uncommon condition and provides a review of previous literature reports with the aim of enhancing the understanding of unusual renal displacement due to massive splenomegaly, and its potential treatment options.
Keyphrases
- computed tomography
- weight loss
- healthcare
- magnetic resonance imaging
- case report
- mental health
- induced apoptosis
- systematic review
- minimally invasive
- single cell
- bariatric surgery
- positron emission tomography
- physical activity
- coronary artery bypass
- adverse drug
- type diabetes
- emergency department
- magnetic resonance
- cell cycle arrest
- cell proliferation
- dual energy
- endoplasmic reticulum stress
- adipose tissue
- cell death
- body mass index
- risk assessment
- gastric bypass
- newly diagnosed
- surgical site infection
- drug induced
- human health