A Nanoparticle-Conjugated Anti-TBK1 siRNA Induces Autophagy-Related Apoptosis and Enhances cGAS-STING Pathway in GBM Cells.

Shengchao XuXi YanLu TangGan DaiChengke Luo

Published in: Evidence-based complementary and alternative medicine : eCAM (2021)

The rGO-PEG could be an efficient system facilitating the delivery of specific siRNA. TBK1si/rGO-PEG could be a novel strategy for the treatment of GBM.

Keyphrases

cell cycle arrest
endoplasmic reticulum stress
induced apoptosis
cell death
oxidative stress
reduced graphene oxide
drug delivery
cancer therapy
signaling pathway
pi k akt
photodynamic therapy
hyaluronic acid
gold nanoparticles
combination therapy
cell proliferation
iron oxide