Atomic force microscopy reveals involvement of the cell envelope in biomechanical properties of sickle erythrocytes.

Kun WangZhiqiang LiOgechukwu EginiRaj WadgaonkarXian-Cheng JiangYong Chen
Published in: BMC biology (2023)
The data reveal that besides the cytosolic hemoglobin fibers, the cell envelope containing the membrane-associated hemoglobin also is involved in the biomechanical properties (e.g., stiffness and shape maintenance) of sickle erythrocytes.