Association of IKZF1 SNPs in cold medicine-related Stevens-Johnson syndrome in Thailand.
Patchima ChantarenPassara JongkhajornpongMayumi UetaVilavun PuangsricharernKaevalin LekhanontPhattrawan PisuchpenPinnita PrabhasawatKanya SuphapeetipornShigeru KinoshitaPublished in: Clinical and translational allergy (2019)
In addition to the Japanese, Korean and Indian populations, Thai cases with CM-SJS/TEN and SOC were significantly associated with IKZF1 SNPs. With our previous report of the critical role of IKZF1 in mucocutaneous inflammation, these results suggest that IKZF1 is important in the pathogenesis of CM-SJS/TEN with SOC.