Germ-free mice are not protected against diet-induced obesity and metabolic dysfunction.

Chiara H MorettiTomas A SchifferXuechen LiEddie WeitzbergMattias CarlstromJon O Lundberg

Published in: Acta physiologica (Oxford, England) (2020)

We provide evidence that the microbiota is not an indispensable factor in the onset of obesity and metabolic dysfunction, suggesting that the relationship between gut bacteria and metabolic diseases needs further exploration.

Keyphrases

high fat diet induced
insulin resistance
metabolic syndrome
weight loss
type diabetes
oxidative stress
weight gain
skeletal muscle