Temporal changes in survival among adult patients with acute myeloid leukaemia in the period 2000-2016: a Danish population-based study.
Lasse Hjort Kyneb JakobsenAnne Stidsholt RougAndreas Kiesbye ØvlisenClaus Werenberg MarcherHans Beier OmmenKim Theilgaard-MönchPeter MøllerClaudia SchöllkopfDaniel KristensenTherese Maria Henriette NaurMartin BøgstedTarec Christoffer El-GalalyMarianne Tang SeverinsenPublished in: British journal of haematology (2020)
In the present study, we quantify the progress in overall survival (OS) during the period 2000-2016 among Danish patients with acute myeloid leukaemia (AML). This population-based study, including 3820 adult patients with AML, demonstrates a significantly improved OS over time with the 2-year age-standardised OS increasing from 22% in 2002 to 31% in 2016. The improvement in OS was exclusively seen in patients with AML aged ≥50 years, with absolute improvements in 2-year OS from 2002 to 2016 of ≥10% among patients aged 50-75 years and a small absolute increase in those aged >75 years.