DNA Photo-cross-linking Using Pyranocarbazole and Visible Light.

Kenzo FujimotoShinobu SasagoJunichi MiharaShigetaka Nakamura

Published in: Organic letters (2018)

This report presents a novel photo-cross-linker that can cross-link to pyrimidines in nucleic acids under visible light irradiation (λ > 400 nm). This method offers ultrafast photo-cross-linking without any cytotoxicity due to UV irradiation.

Keyphrases

visible light
electron transfer
circulating tumor
photodynamic therapy
radiation induced
light emitting