Enrichment of Complement, Immunoglobulins, and Autoantibody Targets in the Proteome of Platelets from Patients with Systemic Lupus Erythematosus.

Carl Petrus LingeAndreas JernHelena TydénBirgitta GullstrandHong YanCharlotte WelinderRobin KahnAndreas JönsenJohn W SempleAnders A Bengtsson

Published in: Thrombosis and haemostasis (2022)

Platelets from SLE patients shared a specific protein profile, including immunoglobulins, complement proteins, and autoantigens, largely independent of the platelet size and in agreement with an integrated role for platelets in SLE.

Keyphrases

systemic lupus erythematosus
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
disease activity
peritoneal dialysis
prognostic factors
rheumatoid arthritis
red blood cell
protein protein
binding protein