Safety and Clinical Response to Combined Immunotherapy with Autologous iNKT Cells and PD-1 + CD8 + T Cells in Patients Failing First-line Chemotherapy in Stage IV Pancreatic Cancer.

Jing Wang Xiaobo Cheng Yanling Jin Bili Xia Ran Qin Wei Zhang Huiliang Hu Xiaoting Mao Liting Zhou Jia Yan Xiaoyan Zhang Jianqing Xu

Published in: Cancer research communications (2023)

T cells in 9 patients with advanced pancreatic cancer and failing the first-line chemotherapy. The combined immunotherapy was shown to be feasible in the enrolled patients with limited side effects and optimistic clinical responses, which could bring opportunity of therapeutic advancement.

Keyphrases

end stage renal disease
ejection fraction
induced apoptosis
chronic kidney disease
newly diagnosed
bone marrow
cell cycle arrest
prognostic factors
mesenchymal stem cells
cell death
patient reported outcomes
endoplasmic reticulum stress
chemotherapy induced