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Is the duration of human pregnancy decreasing? A vision of Darwinian medicine.

Philippe CharlierYves CoppensJacques Hassin
Published in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2020)
Why do actual females have a 9-months-pregnancy? Here, we hypothesize that the pregnancies of prehuman species were longer than currently (10 or 11 months), and that anatomical and metabolic changes, by increasing the in-utero size of the fetal brain, selected groups with premature delivery, low-calcified and/or not welded cranial vault bones (permitting deformation during the expulsion), until reaching a current pregnancy duration of 9 months.
Keyphrases
  • preterm birth
  • pregnancy outcomes
  • endothelial cells
  • pregnant women
  • white matter
  • multiple sclerosis
  • induced pluripotent stem cells
  • blood brain barrier