Enhancing intestinal anastomotic healing using butyrate: Systematic review and meta-analysis of experimental animal studies.

Aurelia C L Wildeboer Claire P M van HelsdingenCamille G GalléRob B M de VriesJoep P M DerikxNicole D Bouvy

Published in: PloS one (2023)

This systematic review and meta-analysis shows that there is potential ground to investigate the use of butyrate in clinical trials to prevent anastomotic leakage in intestinal surgery. However, more research is necessary to define the best application form, dosage and administration route.

Keyphrases

systematic review
rectal cancer
clinical trial
minimally invasive
meta analyses
coronary artery bypass
acute coronary syndrome
case control
phase iii