A novel nanocomposite containing zinc ferrite nanoparticles embedded in carboxymethylcellulose hydrogel plus carbon nitride nanosheets with multifunctional bioactivity.
Fatemeh GanjaliMostafa Ghafori GorabHooman Aghamirza Moghim AliabadiSaman RahmatiReza Ahangari CohanReza Eivazzadeh-KeihanAli MalekiHossein GhafuriMohammad MahdaviPublished in: RSC advances (2023)
A novel and biologically active nanobiocomposite is synthesized based on carbon nitride nanosheet (g-C 3 N 4 ) based carboxymethylcellulose hydrogels with embedded zinc ferrite nanoparticles. Physical-chemical aspects, morphological properties, and their multifunctional biological properties have been considered in the process of evaluation of the synthesized structure. The hydrogels' compressive strength and compressive modulus are 1.98 ± 0.03 MPa and 3.46 ± 0.05 MPa, respectively. Regarding the biological response, it is shown that the nanobiocomposite is non-toxic and biocompatible, and hemocompatible (with Hu02 cells). In addition, the developed material offers a suitable antibacterial activity for both Staphylococcus aureus ( S. aureus ) and Escherichia coli ( E. coli ).
Keyphrases
- drug delivery
- oxide nanoparticles
- reduced graphene oxide
- quantum dots
- escherichia coli
- drug release
- visible light
- staphylococcus aureus
- cancer therapy
- hyaluronic acid
- induced apoptosis
- tissue engineering
- biofilm formation
- gold nanoparticles
- cell cycle arrest
- mental health
- wound healing
- physical activity
- metal organic framework
- extracellular matrix
- highly efficient
- walled carbon nanotubes
- ionic liquid
- pseudomonas aeruginosa
- cell death
- klebsiella pneumoniae
- cell proliferation
- simultaneous determination