Progression of brain cholinergic dysfunction in patients with isolated rapid eye movement sleep behavior disorder.
Kristian StaerAlejandro IranzoMiriam Højholt TerkelsenMorten Gersel StokholmErik Hvid DanielsenKaren ØstergaardMónica SerradellMarit OttoKristina B SvendsenAlicia GarridoDolores VilasJoan SantamariaArne MøllerCarles GaigDavid J BrooksPer BorghammerEduardo TolosaNicola PavesePublished in: European journal of neurology (2023)
Our results show that severity of brain cholinergic dysfunction in iRBD patients increases significantly over 3 years, and those changes are more severe in those with a decline in cognitive test scores.