Correlation between total homocysteine and cerebral small vessel disease: A Mendelian randomization study.

Yuze CaoNing SuDingding ZhangLixin ZhouMing YaoShuyang ZhangLi-Ying CuiYicheng ZhuJun Ni

Published in: European journal of neurology (2021)

Total HCY level was correlated with imaging burden of CSVD, especially with lacunes and brain volume loss. For individuals with risk genetic predisposition, enhanced homocysteine-lowering strategies might be necessary to reduce the risk and progress of CSVD.

Keyphrases

high resolution
subarachnoid hemorrhage
cerebral ischemia
white matter
resting state
brain injury
mass spectrometry
fluorescence imaging