Correlation between total homocysteine and cerebral small vessel disease: A Mendelian randomization study.
Yuze CaoNing SuDingding ZhangLixin ZhouMing YaoShuyang ZhangLi-Ying CuiYicheng ZhuJun NiPublished in: European journal of neurology (2021)
Total HCY level was correlated with imaging burden of CSVD, especially with lacunes and brain volume loss. For individuals with risk genetic predisposition, enhanced homocysteine-lowering strategies might be necessary to reduce the risk and progress of CSVD.