Vitamin D3 suppresses intestinal epithelial stemness via ER stress induction in intestinal organoids.

Panida SittipoHyun Kyu KimJaeseok HanMan Ryul LeeYun Kyung Lee

Published in: Stem cell research & therapy (2021)

Our study provides important insights into the effects of vitamin D3 on the induction of IEC differentiation and apoptotic cell death, and inhibition of intestinal stemness accompanied by ER stress augmentation.

Keyphrases

cell death
stem cells
epithelial mesenchymal transition
signaling pathway
cell cycle arrest
soft tissue
anti inflammatory