Novel investigational treatments for ventilator-associated pneumonia and critically ill patients in the intensive care unit.
Rachael CusackAlexis GardunoKhalid ElkholyIgnacio Martín-LoechesPublished in: Expert opinion on investigational drugs (2022)
The postantibiotic era is rapidly approaching, and the need for personalized medicine, point-of-care microbial sensitivity testing, and development of biomarkers for severe infections is clear. Results from emerging and new antibiotics are encouraging, but infection control measures and de-escalation protocols must be employed to prolong their usefulness in critical illness.