Pharmacological effects of berberine on mood disorders.

Jie Fan Kun Zhang Yang Jin Bingjini Li Shuohui Gao Jiaming Zhu Ran Ji Cui

Published in: Journal of cellular and molecular medicine (2018)

Berberine, a natural isoquinoline alkaloid, is used in herbal medicine and has recently been shown to have efficacy in the treatment of mood disorders. Furthermore, berberine modulates neurotransmitters and their receptor systems within the central nervous system. However, the detailed mechanisms of its action remain unclear. This review summarizes the pharmacological effects of berberine on mood disorders. Therefore, it may be helpful for potential application in the treatment of mood disorders.

Keyphrases

bipolar disorder
sleep quality
climate change
physical activity
binding protein