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Rapid generation of monocyte-derived antigen-presenting cells with dendritic cell-like properties.

Sarah CunninghamHolger Hackstein
Published in: Transfusion (2021)
Our results indicate that mature 36 h MoAPCs possess DC-like capabilities by inducing antigen-specific T cell responses. This study has important implications for the generation of DC-based cellular therapies, allowing a more cost and time-efficient generation of APCs.
Keyphrases
  • dendritic cells
  • regulatory t cells
  • immune response
  • cell cycle arrest
  • case report
  • oxidative stress
  • peripheral blood
  • endoplasmic reticulum stress
  • sensitive detection