A non-retinol retinoic acid receptor-γ (RAR-γ/NR1B3) selective agonist, tectorigenin, can effectively inhibit the ultraviolet A-induced skin damage.

Xintong DaiJing JinYan JiaKai YangJingxia HanZhiyuan ZhangXiujuan DingCheng YaoTao SunCaibin ZhuHui-Juan Liu

Published in: British journal of pharmacology (2022)

Tectorignen is a non-retinol RAR-γ-selective agonist that can inhibit UV-induced skin damage and could be developed as a safe pharmaceutical component for the prevention of photoaging and skin inflammation.

Keyphrases

oxidative stress
diabetic rats
soft tissue
high glucose
wound healing
drug induced
endothelial cells
binding protein