Plasma interferon-γ-inducible protein 10 (IP-10) levels correlate with disease severity and paradoxical reactions in extrapulmonary tuberculosis.
Isabelle SuárezSamuel RohrMelanie StecherClara LehmannSandra WinterNorma JungVanessa PriesnerMelanie BergerChristoph WyenMax AugustinJakob J MalinJulia FischerCarola HornFlorian NeuhannMichael PüskenGeorg PlumGerd FätkenheuerJan RybnikerPublished in: Infection (2020)
Our data demonstrate that IP-10 may be a valuable biomarker for estimation of disease severity in EPTB and monitoring of the disease course in extensive forms. However, IP-10 may be less suitable for diagnosis and monitoring of EPTB patients with limited disease. The QFT® Plus test does not appear to be a suitable marker for therapy monitoring. Sputum should be examined in EPTB patients even in case of normal diagnostic imaging of the chest.
Keyphrases
- end stage renal disease
- mycobacterium tuberculosis
- chronic kidney disease
- pulmonary tuberculosis
- newly diagnosed
- high resolution
- cystic fibrosis
- stem cells
- emergency department
- big data
- hiv aids
- artificial intelligence
- binding protein
- mass spectrometry
- hepatitis c virus
- hiv infected
- deep learning
- fluorescence imaging