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Structural changes, increased hypoxia, and oxidative DNA damage in placenta due to maternal smokeless tobacco use.

Shashi Nandar KumarBanajit BastiaDeepa BorgohainUsha AgrawalSheikh RaisuddinArun Kumar Jain
Published in: Birth defects research (2021)
Maternal SLT exposure during pregnancy may be associated with villus hypoxia and consequently oxidative DNA damage. It is presumed that deleterious effect of SLT exposure on placenta could result in impairment of placental barrier, and restrict nutrient and oxygen supply from mother to fetus, and thus could be a cause of fetal growth restriction.
Keyphrases
  • dna damage
  • oxidative stress
  • dna repair
  • birth weight
  • endothelial cells
  • pregnancy outcomes
  • pregnant women
  • physical activity
  • weight gain
  • weight loss
  • preterm birth