Association of variants in the ATXN2 (rs7137828), FOXC1 (rs2745572) and TXNRD2 (rs35934224) genes as risk factors for primary open-angle glaucoma development in a Brazilian cohort.
Thiago Adalton Rosa RodriguesBruno Batista de SouzaVictor de Haidar E BertozzoJúlia Nicoliello Pereira de CastroAna Carolina Lima CamargoFernando Ferreira CostaRui Barroso SchimitiVital Paulino CostaFernanda Maria Silveira SoutoMônica Barbosa de MeloPublished in: Ophthalmic genetics (2023)
Our data indicate the rs7137828 associated with increased risk for the development of POAG and VCDR in a Brazilian cohort. If validated in additional populations, these findings may enable the development of relevant strategies for early diagnosis of glaucoma in the future.