Thymidylate synthase drives the phenotypes of epithelial-to-mesenchymal transition in non-small cell lung cancer.
Mohammad Aarif SiddiquiParadesi Naidu GollavilliVignesh RameshBeatrice ParmaAnnemarie SchwabMaria Eleni VazakidouRamakrishnan NatesanOzge SaatciIda RapaPaolo BironzoHarald SchuhwerkIrfan Ahmed AsanganiOzgur SahinMarco VolantePaolo CeppiPublished in: British journal of cancer (2020)
These results establish TS as a theranostic NSCLC marker integrating survival, chemo-resistance and EMT, and identifies a regulatory network that could be targeted in EMT-driven NSCLC.
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