Single-Cell Transcriptomics Reveals Evidence of Endothelial Dysfunction in the Brains of COVID-19 Patients with Implications for Glioblastoma Progression.

Abhimanyu ThakurLifan LiangSourav Banerjee Kui Zhang

Published in: Brain sciences (2023)

The results indicate a significant overlap between COVID-19 and GBM in the context of endothelial dysfunction, suggesting that there may be an endothelial dysfunction link connecting severe SARS-CoV-2 infection in the brain to GBM progression.

Keyphrases

single cell
sars cov
rna seq
coronavirus disease
respiratory syndrome coronavirus
high throughput
early onset
resting state
white matter
functional connectivity
subarachnoid hemorrhage
blood brain barrier