Differential effects of lung inflammation on insulin resistance in humans and mice.

Ruth KarlinaClaudia FlexederStephanie MusiolMadhumita BhattacharyyaEvelyn SchneiderIrem AltunSilvia GschwendtnerAvidan U NeumannJana NanoMichael SchloterAnnette PetersHolger SchulzCarsten B Schmidt-Weber Marie StandlClaudia Traidl-HoffmannFrancesca Alessandrini Siegfried Ussar

Published in: Allergy (2022)

Asthma associates with insulin resistance in humans, but HDM challenge results in opposing effects on glucose homeostasis in mice due to increased energy expenditure, reduced adipose inflammation, and hepatosteatosis.

Keyphrases

oxidative stress
high fat diet induced
insulin resistance
chronic obstructive pulmonary disease
adipose tissue
lung function
wild type
blood pressure
cystic fibrosis
skeletal muscle