Focal therapy for prostate cancer.
Sana BasseriNathan PerlisSangeet GhaiPublished in: Abdominal radiology (New York) (2024)
Traditional treatments for localized prostate cancer include radical prostatectomy or radiation therapy but pose challenges due to treatment related side effects, namely erectile dysfunction and urinary incontinence. In recent years, focal therapy has emerged as a viable treatment option for localized low-intermediate risk prostate cancer in carefully selected patients. Short and medium-term studies show acceptable cancer control outcomes and reduced morbidity when comparing focal therapy to whole gland treatment for prostate cancer, however there is paucity of long-term studies. Here we review focal ablative therapies commonly used, discuss the role of imaging in monitoring treatment, and summarize oncologic outcomes based on studies to date.
Keyphrases
- prostate cancer
- radical prostatectomy
- end stage renal disease
- urinary incontinence
- type diabetes
- adipose tissue
- combination therapy
- chronic kidney disease
- squamous cell carcinoma
- skeletal muscle
- replacement therapy
- photodynamic therapy
- weight loss
- minimally invasive
- patient reported outcomes
- bone marrow
- peritoneal dialysis
- radiation induced
- rectal cancer
- lymph node metastasis
- cell therapy