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Effects of helminths and anthelmintic treatment on cardiometabolic diseases and risk factors: A systematic review.

Khanh PhamAnna MertelsmannKeith MagesJustin R KingeryHumphrey D MazigoHyasinta JakaFredrick KalokolaJohn M ChangaluchaSaidi KapigaRobert N PeckJennifer A Downs
Published in: PLoS neglected tropical diseases (2023)
Helminth infections may offer protection against dyslipidemia, metabolic syndrome, diabetes, and atherosclerotic cardiovascular disease. This protection may lessen after anthelmintic treatment. Our findings highlight the need for mechanistic trials to determine the pathways linking helminth infections with cardiometabolic diseases. Such studies could have implications for helminth eradication campaigns and could generate new strategies to address the global challenge of cardiometabolic diseases.
Keyphrases
  • cardiovascular disease
  • metabolic syndrome
  • risk factors
  • type diabetes
  • insulin resistance
  • helicobacter pylori infection
  • uric acid
  • helicobacter pylori
  • glycemic control
  • smoking cessation