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Breaking the mold: a case of recalcitrant eyelid subconjunctival infection by Exophilia Phaeomuriformis.

Colin P FroinesNathe ConnorEmily LiRebecca A YodaLuis Francisco Gonzalez-CuyarG Nina LuRoxana FuMatthew Zhang
Published in: Orbit (Amsterdam, Netherlands) (2021)
While a rare ophthalmic pathogen, infections from Exophilia spp. are increasingly identified and have been associated with catastrophic vision loss. In this case report we present a previously undescribed manifestation of the melanin-producing fungus Exophilia Phaeomuriformis to the lower eyelid, establish an effective treatment, and review related cases. Previous cases of ophthalmic E. Phaeomuriformis were confined to the cornea and included iatrogenic tissue trauma. This case shares neither associations however includes a remote SJS history that likely led to changes in conjunctival tissue integrity. Previous cases of Exophilia spp. infecting the eyelid both included surgical source control and adjuvant antibiotic. In this case, topical therapy was deferred due to SJS-related ocular cicatricial disease. Fortunately, a full resolution was achieved with surgical resection and oral antifungal treatment.
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