Effects of rs958804 and rs7858836 single-nucleotide polymorphisms of the ASTN2 gene on pain-related phenotypes in patients who underwent laparoscopic colectomy and mandibular sagittal split ramus osteotomy.

Rie InoueDaisuke NishizawaJunko HasegawaKyoko NakayamaKen-Ichi FukudaTatsuya IchinoheTsutomu MiedaMiki TsujitaHideyuki NakagawaAkira KitamuraHiroyuki SumikuraAnd Kazutaka IkedaMasakazu Hayashida

Published in: Neuropsychopharmacology reports (2021)

The two SNPs of the ASTN2 gene were consistently associated with fentanyl requirements after two different types of surgery. These findings may contribute to personalized pain control.

Keyphrases

chronic pain
genome wide
end stage renal disease
pain management
neuropathic pain
ejection fraction
copy number
minimally invasive
chronic kidney disease
peritoneal dialysis
dna methylation
coronary artery bypass
spinal cord injury