Impact of different palliative systemic treatments on skeletal muscle mass in metastatic colorectal cancer patients.

Sophie Alberdine KurkPetra H M PeetersBram DorresteijnPim A de JongMarion JourdanHugo J KuijfCornelis J A PuntMiriam KoopmanAnne M May

Published in: Journal of cachexia, sarcopenia and muscle (2018)

This longitudinal study provides a unique insight in SMM changes in mCRC patients during palliative systemic treatment regimens, including observation. Our data show that muscle loss is reversible and may be influenced by the intensity of systemic regimens. Although studies have shown prognostic capacity for SMM, the effects of subsequent changes in SMM are unknown and may be clues for new future therapeutic interventions.

Keyphrases

end stage renal disease
skeletal muscle
chronic kidney disease
newly diagnosed
ejection fraction
peritoneal dialysis
metastatic colorectal cancer
palliative care
physical activity
metabolic syndrome
patient reported outcomes
big data
artificial intelligence
smoking cessation