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Transcription factors early growth response gene (Egr) 2 and 3 control inflammatory responses of tolerant T cells.

Becky OmodhoTizong MiaoAlistair L J SymondsRandeep SinghSuling LiPing Wang
Published in: Immunity, inflammation and disease (2018)
Our findings demonstrated that despite impaired proliferation and IL2 production, tolerant T cells can display inflammatory responses in response to antigen stimulation and this is controlled at least partly by Egr2 and 3.
Keyphrases
  • transcription factor
  • genome wide identification
  • signaling pathway
  • copy number
  • genome wide
  • dna methylation