Transcription factors early growth response gene (Egr) 2 and 3 control inflammatory responses of tolerant T cells.
Becky OmodhoTizong MiaoAlistair L J SymondsRandeep SinghSuling LiPing WangPublished in: Immunity, inflammation and disease (2018)
Our findings demonstrated that despite impaired proliferation and IL2 production, tolerant T cells can display inflammatory responses in response to antigen stimulation and this is controlled at least partly by Egr2 and 3.