Helicobacter pylori and its secreted immunomodulator VacA protect against anaphylaxis in experimental models of food allergy.
A KyburzS UrbanA AltobelliS FloessJ HuehnT L CoverAnne MüllerPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2017)
Helicobacter pylori confers protection against the anaphylaxis associated with ovalbumin and peanut allergy and affects the epigenome of T cells, thereby promoting stable Treg differentiation and functionality. Prophylactic treatment with H. pylori-derived immunomodulators appears to be a promising strategy for food allergy prevention.