ATRX loss promotes immunosuppressive mechanisms in IDH1 mutant glioma.

Chengchen HuKimberly WangCeylan DamonYi FuTengjiao MaLisa KratzBachchu LalMingyao YingShuli XiaDaniel P CahillChristopher M JacksonMichael LimJohn LaterraYunqing Li

Published in: Neuro-oncology (2022)

ATRX loss activates a BRD-dependent immune-suppressive transcriptome and immune escape mechanism in IDH1R132H/p53mut astrocytoma cells.

Keyphrases

wild type
induced apoptosis
low grade
cell cycle arrest
gene expression
rna seq
genome wide
endoplasmic reticulum stress
signaling pathway
oxidative stress
cell death
dna methylation
cell proliferation