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ATRX loss promotes immunosuppressive mechanisms in IDH1 mutant glioma.

Chengchen HuKimberly WangCeylan DamonYi FuTengjiao MaLisa KratzBachchu LalMingyao YingShuli XiaDaniel P CahillChristopher M JacksonMichael LimJohn LaterraYunqing Li
Published in: Neuro-oncology (2022)
ATRX loss activates a BRD-dependent immune-suppressive transcriptome and immune escape mechanism in IDH1R132H/p53mut astrocytoma cells.
Keyphrases
  • wild type
  • induced apoptosis
  • low grade
  • cell cycle arrest
  • gene expression
  • rna seq
  • genome wide
  • endoplasmic reticulum stress
  • signaling pathway
  • oxidative stress
  • cell death
  • dna methylation
  • cell proliferation