CSF P-Tau181 and Other Biomarkers in Patients With Neuronal Intranuclear Inclusion Disease.
Masanori KuriharaHiroki KomatsuRenpei SengokuMari ShibukawaSatoru MorimotoTomoyasu MatsubaraAkira ArakawaMakoto OritaKenji IshibashiAkihiko MitsutakeShota ShibataHiroyuki IshiuraKaori AdachiKensuke OhseKeiko HatanoRyoko IharaMana HigashiharaYasushi NishinaAya Midori TokumaruKenji IshiiYuko SaitoShigeo MurayamaKazutomi KanemaruAtsushi IwataPublished in: Neurology (2022)
CSF p-tau181 was increased in patients with NIID without amyloid accumulation. Although the deposition of p-tau has not been reported in NIID brains, the molecular mechanism of tau phosphorylation or secretion of p-tau may be altered in NIID.
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